diff --git a/Data/nix/WineOnArm/shell.nix b/Data/nix/WineOnArm/shell.nix
new file mode 100644
index 000000000..04b76365a
--- /dev/null
+++ b/Data/nix/WineOnArm/shell.nix
@@ -0,0 +1,52 @@
+{ pkgs ? import <nixpkgs> { } }:
+
+let
+  toolchain = pkgs.fetchzip {
+    url = "https://github.com/bylaws/llvm-mingw/releases/download/20250305/llvm-mingw-20250305-ucrt-ubuntu-20.04-aarch64.tar.xz";
+    sha256 = "sha256-cA03/ab9O61eO9+S2JzIXD4V0HzTXK5/AYyxW2d73Po=";
+  };
+
+  cmakeToolchainFile = pkgs.substitute {
+    # Use absolute paths that are discoverable outside of the nix shell
+    src = ../../CMake/toolchain_mingw.cmake;
+    substitutions = ["--replace-fail" "\${MINGW_TRIPLE}-" "${toolchain}/bin/\${MINGW_TRIPLE}-"];
+  };
+
+  mesonCrossFile = pkgs.writeText "crossfile_llvm_mingw.txt" ''
+    [binaries]
+    ar = '${toolchain}/bin/arm64ec-w64-mingw32-ar'
+    c = '${toolchain}/bin/arm64ec-w64-mingw32-gcc'
+    cpp = '${toolchain}/bin/arm64ec-w64-mingw32-g++'
+    ld = '${toolchain}/bin/arm64ec-w64-mingw32-ld'
+    windres = '${toolchain}/bin/arm64ec-w64-mingw32-windres'
+    strip = '${toolchain}/bin/strip'
+    widl = '${toolchain}/bin/arm64ec-w64-mingw32-widl'
+    pkgconfig = 'aarch64-linux-gnu-pkg-config'
+    [host_machine]
+    system = 'windows'
+    cpu_family = 'aarch64'
+    cpu = 'aarch64'
+    endian = 'little'
+  '';
+in
+pkgs.mkShell {
+  buildInputs = [
+    toolchain
+  ];
+
+  shellHook = ''
+    if [[ $- == *i* ]]; then
+      echo "llvm-mingw set up at ${toolchain}."
+      echo ""
+      echo "To configure DXVK/vkd3d-proton: meson setup \$FEX_MESON_CROSSFILE"
+      echo ""
+      echo "To configure 32-bit FEX build: cmake \$FEX_CMAKE_TOOLCHAIN_WOW64"
+      echo "To configure 64-bit FEX build: cmake \$FEX_CMAKE_TOOLCHAIN_ARM64EC"
+    fi
+  '';
+
+  # E.g. cmake $FEX_CMAKE_TOOLCHAIN_ARM64EC -DCMAKE_BUILD_TYPE=Release -DCMAKE_INSTALL_PREFIX=/usr -DENABLE_LTO=False -DBUILD_TESTS=False
+  FEX_CMAKE_TOOLCHAIN_ARM64EC = "--toolchain ${cmakeToolchainFile} -DMINGW_TRIPLE=arm64ec-w64-mingw32 -DCMAKE_INSTALL_LIBDIR=/usr/lib/wine/aarch64-windows";
+  FEX_CMAKE_TOOLCHAIN_WOW64 = "--toolchain ${cmakeToolchainFile} -DMINGW_TRIPLE=aarch64-w64-mingw32 -DCMAKE_INSTALL_LIBDIR=/usr/lib/wine/aarch64-windows";
+  FEX_MESON_CROSSFILE = "--cross-file ${mesonCrossFile}";
+}
diff --git a/Data/nix/cmake_configure_woa32.sh b/Data/nix/cmake_configure_woa32.sh
new file mode 100755
index 000000000..45295cacc
--- /dev/null
+++ b/Data/nix/cmake_configure_woa32.sh
@@ -0,0 +1,21 @@
+#! /usr/bin/env nix-shell
+#! nix-shell -i bash WineOnArm/shell.nix
+
+# Helper script to configure CMake for building FEX as library for emulation
+# of 32-bit applications in Wine/Proton.
+# The required cross-toolchains will be set up and managed by nix.
+
+if [ $# -eq 0 ]
+then
+  echo "Expected CMake argument list"
+  exit 1
+fi
+
+if [ -f CMakeCache.txt ]
+then
+  echo "Expected empty build folder"
+  exit 1
+fi
+
+set -o xtrace
+cmake $FEX_CMAKE_TOOLCHAIN_WOW64 -DCMAKE_BUILD_TYPE=Release -DCMAKE_INSTALL_PREFIX=/usr -DENABLE_LTO=False -DBUILD_TESTS=False $@
diff --git a/Data/nix/cmake_configure_woa64.sh b/Data/nix/cmake_configure_woa64.sh
new file mode 100755
index 000000000..1a8f5f230
--- /dev/null
+++ b/Data/nix/cmake_configure_woa64.sh
@@ -0,0 +1,21 @@
+#! /usr/bin/env nix-shell
+#! nix-shell -i bash WineOnArm/shell.nix
+
+# Helper script to configure CMake for building FEX as library for emulation
+# of 64-bit applications in Wine/Proton
+# Nix is used to install and manage the required cross-toolchains.
+
+if [ $# -eq 0 ]
+then
+  echo "Expected CMake argument list"
+  exit 1
+fi
+
+if [ -f CMakeCache.txt ]
+then
+  echo "Expected empty build folder"
+  exit 1
+fi
+
+set -o xtrace
+cmake $FEX_CMAKE_TOOLCHAIN_ARM64EC -DCMAKE_BUILD_TYPE=Release -DCMAKE_INSTALL_PREFIX=/usr -DENABLE_LTO=False -DBUILD_TESTS=False $@